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Medical Research Platforms

timsTOF HT

timsTOF HT

timsTOF HT is a high-end mass spectrometer launched by Bruker, featuring the fourth-generation TIMS-XR analyzer and advanced digital conversion technology. It is specifically designed for high-throughput quantitative cell and tissue proteomics analysis. This device enables a wider dynamic range and higher protein coverage depth in quantitative proteomics analysis, making it particularly suitable for 4D-proteomics technology.

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Product Advantages

High throughput and depth

High sensitivity

Wide dynamic range

High stability

Integrated with the fourth-generation TIMS-XR analyzer and advanced digital conversion technology

Product Applications

Proteomics research: Suitable for quantitative proteomics analysis of cells and tissues, especially outstanding in high-throughput 4D-proteomics.
Single-cell proteomics: Combined with the CellenONE PICO liquid dispensing system to advance single-cell proteomics applications.
Clinical proteomics: Suitable for the analysis of tissue slices and biopsy samples, especially for clinical proteomics research involving highly heterogeneous cell populations.

Product Specifications

Dynamic Range

Scanning Speed

Sensitivity

Stability

The timsTOF HT can identify over 100,000 peptide sequences (1% FDR) within 60 minutes with a 1 µg protein sample injection

Using PASEF® technology, the scanning speed reaches up to 300 Hz without compromising resolution and sensitivity

The ultra-large ion capacity of the fourth-generation TIMS-XR significantly enhances analysis depth

The correlation of protein identification from three replicate analyses of the same sample is as high as 99%, with a CV value below 5%