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timsTOF flex MALDI-2

timsTOF flex MALDI-2

The timsTOF flex MALDI-2 is based on time-of-flight (TOF) mass spectrometry, integrated with the MALDI-2 (Matrix-Assisted Laser Desorption/Ionization-2) post-ionization technique. This technology significantly enhances ionization efficiency and sensitivity by using a second laser pulse for post-ionization of neutral molecules, addressing issues of ion suppression and low sensitivity inherent in traditional MALDI methods.

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Product Advantages

High sensitivity

Ultra-high spatial imaging resolution

High throughput

Product Applications

-Drug metabolism research: MALDI-2 improves the localization accuracy of drugs and metabolites in tissues, suitable for quantification across a wider dose range.
-Single-cell imaging: With microGRID technology, timsTOF flex MALDI-2 enables fine imaging experiments with single-cell resolution, ideal for subcellular structure analysis in biological and medical research.
-Multi-omics research: In lipidomics and metabolomics, MALDI-2 allows detection of more compound types, helping to understand the complexity of nature.

Product Specifications

Sensitivity

Optimal mass resolution

Spatial imaging resolution

TIMS Resolution

Mass accuracy

fmol level

> 60,000 (at m/z 200)

5-10 μm

200-300

< 200 ppb (internal standard), < 1 ppm (external standard)